Shroom 3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q8TF72 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 216857 Da |
Gene ID | 57619 |
---|---|
Other Names | Protein Shroom3, Shroom-related protein, hShrmL, SHROOM3, KIAA1481, SHRML |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | SHROOM3 |
---|---|
Synonyms | KIAA1481, SHRML |
Function | Controls cell shape changes in the neuroepithelium during neural tube closure. Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myosin II, and probably by bundling stress fibers (By similarity). Induces apicobasal cell elongation by redistributing gamma-tubulin and directing the assembly of robust apicobasal microtubule arrays (By similarity). |
Cellular Location | Cell junction, adherens junction {ECO:0000250|UniProtKB:Q9QXN0}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9QXN0}. Apical cell membrane {ECO:0000250|UniProtKB:Q9QXN0}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QXN0}. Note=Colocalizes with F-actin in stress fibers and adherens junctions. {ECO:0000250|UniProtKB:Q9QXN0} |
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