SPINK2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | P20155 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 9291 Da |
Gene ID | 6691 |
---|---|
Other Names | Serine protease inhibitor Kazal-type 2, Acrosin-trypsin inhibitor, Epididymis tissue protein Li 172, HUSI-II, SPINK2 |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | SPINK2 |
---|---|
Function | As a strong inhibitor of acrosin, it is required for normal spermiogenesis. It probably hinders premature activation of proacrosin and other proteases, thus preventing the cascade of events leading to spermiogenesis defects (PubMed:28554943). May be involved in the regulation of serine protease-dependent germ cell apoptosis (By similarity). It also inhibits trypsin. |
Cellular Location | Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome |
Tissue Location | Expressed in epididymis (at protein level). |
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