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MRVI1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC |
|---|---|
| Primary Accession | Q9Y6F6 |
| Reactivity | Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 97957 Da |
| Gene ID | 10335 |
|---|---|
| Other Names | Inositol 1, 4, 5-triphosphate receptor associated 1, Inositol 1, 4, 5-trisphosphate receptor-associated cGMP kinase substrate, JAW1-related protein MRVI1, Protein MRVI1, IRAG1 (HGNC:7237), IRAG, JAW1L, MRVI1 |
| Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | IRAG1 (HGNC:7237) |
|---|---|
| Synonyms | IRAG, JAW1L, MRVI1 |
| Function | Plays a role as NO/PRKG1-dependent regulator of IP3-induced calcium release; its phosphorylation by PRKG1 inhibits bradykinin and IP3-induced calcium release from intracellular stores. Recruits PRKG1 to the endoplasmic reticulum and may mediate the assembly of PRKG1 and ITPR1 in a macrocomplex. Involved in PRKG1 signaling cascade leading to inhibition of platelet activation and aggregation. Mediates also NO- dependent inhibition of calcium signaling in gastrointestinal smooth muscle contributing to NO-dependent relaxation. |
| Cellular Location | Cytoplasm, perinuclear region. Sarcoplasmic reticulum. Membrane; Single-pass membrane protein |
| Tissue Location | Expressed in the colon, rectum, and cultured colonic smooth muscle. Detected in various cancer cell lines |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP56856
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