MACROD2/C20orf133 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
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Primary Accession | A1Z1Q3 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 47421 Da |
Gene ID | 140733 |
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Other Names | ADP-ribose glycohydrolase MACROD2, MACRO domain-containing protein 2, O-acetyl-ADP-ribose deacetylase MACROD2, 3.5.1.-, [Protein ADP-ribosylaspartate] hydrolase MACROD2, 3.2.2.-, [Protein ADP-ribosylglutamate] hydrolase MACROD2, 3.2.2.-, MACROD2 {ECO:0000303|PubMed:23474712, ECO:0000312|HGNC:HGNC:16126} |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MACROD2 {ECO:0000303|PubMed:23474712, ECO:0000312|HGNC:HGNC:16126} |
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Function | Removes ADP-ribose from aspartate and glutamate residues in proteins bearing a single ADP-ribose moiety (PubMed:23474714, PubMed:23474712). Inactive towards proteins bearing poly-ADP-ribose (PubMed:23474714, PubMed:23474712). Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins (PubMed:21257746). |
Cellular Location | Nucleus. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins. |
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