MAMDC2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, ICC, E |
---|---|
Primary Accession | Q7Z304 |
Reactivity | Rat, Pig, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 75 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human MAMDC2 |
Epitope Specificity | 601-686/686 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Secreted > extracellular space > extracellular matrix. |
SIMILARITY | Contains 4 MAM domains. |
Post-translational modifications | O-glycosylated. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | MAMDC2 is a 686 amino acid secreted protein that localizes to extracellular matrix. Containing four MAM domains and existing as two alternatively spliced isoforms, MAMDC2 is encoded by a gene located on human chromosome 9q21.11. Chromosome 9 consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Considered to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, Familial dysautonomia and certain leukemias are also associated with chromosome 9. |
Gene ID | 256691 |
---|---|
Other Names | MAM domain-containing protein 2, MAM domain-containing proteoglycan, Mamcan, MAMDC2 |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MAMDC2 |
---|---|
Cellular Location | Secreted, extracellular space, extracellular matrix |

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