MAP17 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q13113 |
Reactivity | Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 33 KDa |
Physical State | Liquid |
Immunogen | KLH conjugated synthetic peptide derived from human MAP17 |
Epitope Specificity | 51-114/114 |
Isotype | IgG |
Purity | affinity purified by Protein A |
Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
SUBCELLULAR LOCATION | Membrane; Single-pass membrane protein. |
SUBUNIT | Interacts with PDZK1. |
Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
Background Descriptions | MAP17 is a 17 kDa membrane-associated protein expressed abundantly in carcinomas arising from kidney, colon, lung, and breast. In normal tissues it is expressed in significant amounts in the kidney. |
Gene ID | 10158 |
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Other Names | PDZK1-interacting protein 1, 17 kDa membrane-associated protein, Protein DD96, PDZK1IP1, MAP17 |
Target/Specificity | Expressed at significant levels only in a single epithelial cell population, the proximal tubular epithelial cells of the kidney. Diffusely expressed in various carcinomas originating from kidney, colon, lung and breast. |
Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500 |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | PDZK1IP1 (HGNC:16887) |
---|---|
Function | Auxiliary protein of electrogenic Na(+)-coupled sugar symporter SLC5A2/SGLT2 and SLC5A1/SGLT1 (PubMed:34880493, PubMed:37217492, PubMed:38057552). Essential for the transporter activity of SLC5A2/SGLT2 but not SLC5A1/SGLT1 (PubMed:37217492). |
Cellular Location | Apical cell membrane; Single-pass membrane protein |

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