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> home > Products > Primary Antibodies > Signal Transduction > MBIP/MAP3K12 binding inhibitory protein 1 Polyclonal Antibody
MBIP/MAP3K12 binding inhibitory protein 1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q9NS73 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human MBIP/MAP3K12 binding inhibitory protein 1 |
| Epitope Specificity | 151-250/344 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Nucleus. Cytoplasm. Shows a cytoplasmic localization when coexpressed with MAP3K12. |
| SUBUNIT | Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. In the complex, it probably interacts directly with KAT2A, CSRP2BP and WDR5. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 51562 |
|---|---|
| Other Names | MAP3K12-binding inhibitory protein 1, MAPK upstream kinase-binding inhibitory protein, MUK-binding inhibitory protein, MBIP |
| Target/Specificity | Ubiquitous. High expression seen in the heart and lung. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | MBIP |
|---|---|
| Function | Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. |
| Cellular Location | Nucleus. Cytoplasm. Note=Shows a cytoplasmic localization when coexpressed with MAP3K12 |
| Tissue Location | Ubiquitous. High expression seen in the heart and lung |
Research Areas
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$ 385.00
Cat# AP57208
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