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DHB13 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P-Leica, E |
|---|---|
| Primary Accession | Q7Z5P4 |
| Other Accession | NP_835236.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 33655 Da |
| Antigen Region | 81-110 aa |
| Gene ID | 345275 |
|---|---|
| Other Names | 17-beta-hydroxysteroid dehydrogenase 13, 17-beta-HSD 13, 11--, Short-chain dehydrogenase/reductase 9, HSD17B13, SCDR9 |
| Target/Specificity | This DHB13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the N-terminal region of human DHB13. |
| Dilution | WB~~1:1000 IHC-P-Leica~~1:500 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DHB13 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HSD17B13 (HGNC:18685) |
|---|---|
| Function | Plays a pivotal role in hepatic lipid metabolism (PubMed:29562163). In vitro, it catalyzes the oxidation of a variety of lipid substrates, including 17beta-estradiol, retinol, retinal, and leukotriene B4 (PubMed:29562163, PubMed:30415504, PubMed:32973038). |
| Cellular Location | [Isoform 2]: Lipid droplet. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VCR2}. Note=Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation. {ECO:0000250|UniProtKB:Q8VCR2} |
| Tissue Location | Highly expressed in the liver (PubMed:29562163). Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Persson, B., et al. Chem. Biol. Interact. 178 (1-3), 94-98 (2009) :
Liu, S., et al. Acta Biochim. Pol. 54(1):213-218(2007)
Yamada, S., et al. Oncogene 23(35):5901-5911(2004)
Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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