PRRT1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q99946 |
Reactivity | Rat, Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 31430 Da |
Gene ID | 80863 |
---|---|
Other Names | Proline-rich transmembrane protein 1, Dispanin subfamily D member 1, DSPD1, Synapse differentiation-induced protein 4, PRRT1 (HGNC:13943) |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | PRRT1 (HGNC:13943) |
---|---|
Function | Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q6MG82}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q6MG82} Synapse {ECO:0000250|UniProtKB:Q6MG82} |
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