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SEZ6L2 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q6UXD5 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 98 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SEZ6L2 |
| Epitope Specificity | 801-910/910 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Cell membrane. Endoplasmic reticulum membrane. Detected on cell surface of lung-cancer. |
| SIMILARITY | Belongs to the SEZ6 family. Contains 3 CUB domains. Contains 5 Sushi (CCP/SCR) domains. |
| Post-translational modifications | O-glycosylated with core 1 or possibly core 8 glycans. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | This gene encodes a seizure-related protein that is localized on the cell surface. The gene is located in a region of chromosome 16p11.2 that is thought to contain candidate genes for autism spectrum disorders (ASD), though there is no evidence directly implicating this gene in ASD. Increased expression of this gene has been found in lung cancers, and the protein is therefore considered to be a novel prognostic marker for lung cancer. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
| Gene ID | 26470 |
|---|---|
| Other Names | Seizure 6-like protein 2, SEZ6L2, PSK |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | SEZ6L2 |
|---|---|
| Synonyms | PSK |
| Function | May contribute to specialized endoplasmic reticulum functions in neurons. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=Detected on cell surface of lung- cancer |
Research Areas
Citations (0)
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Application Protocols
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$ 385.00
Cat# AP57870
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