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RANBP17 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q9H2T7 |
| Reactivity | Rat, Pig, Chimpanzee, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 124 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human RANBP17 |
| Epitope Specificity | 1001-1088/1088 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| SUBCELLULAR LOCATION | Cytoplasm. Nucleus. Nucleus > nuclear pore complex. |
| SIMILARITY | Belongs to the exportin family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002] |
| Gene ID | 64901 |
|---|---|
| Other Names | Ran-binding protein 17, RANBP17 |
| Target/Specificity | Highly expressed in testis, moderately in pancreas and weakly in other tissues studied. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | RANBP17 |
|---|---|
| Function | May function as a nuclear transport receptor. |
| Cellular Location | Cytoplasm. Nucleus. Nucleus, nuclear pore complex |
| Tissue Location | Highly expressed in testis, moderately in pancreas and weakly in other tissues studied. |
Research Areas
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Application Protocols
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$ 385.00
Cat# AP57904
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