SH3D19 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q5HYK7 |
Reactivity | Rat, Dog, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 86525 Da |
Gene ID | 152503 |
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Other Names | SH3 domain-containing protein 19, ADAM-binding protein Eve-1, EEN-binding protein, EBP, SH3D19 |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | SH3D19 |
---|---|
Function | May play a role in regulating A disintegrin and metalloproteases (ADAMs) in the signaling of EGFR-ligand shedding. May be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1. Plays a role in the regulation of cell morphology and cytoskeletal organization. |
Cellular Location | Cytoplasm. Nucleus. Note=Is recruited to the nucleus by the KMT2A/MLL1-EEN fusion protein |
Tissue Location | Widely expressed with highest levels in heart, skeletal muscle, kidney, liver, placenta, small intestine and lung Expressed at low levels in colon, thymus, spleen and leukocytes |
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