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SLC38A5 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC |
|---|---|
| Primary Accession | Q8WUX1 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 51457 Da |
| Gene ID | 92745 |
|---|---|
| Other Names | Sodium-coupled neutral amino acid transporter 5, Solute carrier family 38 member 5, System N transporter 2, SLC38A5, JM24, SN2, SNAT5 |
| Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100, |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | SLC38A5 |
|---|---|
| Synonyms | JM24, SN2 {ECO:0000303|PubMed:11243884}, |
| Function | Symporter that cotransports neutral amino acids and sodium ions, coupled to an H(+) antiporter activity (PubMed:11243884). Releases L-glutamine and glycine from astroglial cells and may participate in the glutamate/GABA-L-glutamine cycle and the NMDA receptors activation (By similarity). In addition, contributes significantly to L-glutamine uptake in retina, namely in ganglion and Mueller cells therefore, participates in the retinal glutamate- glutamine cycle (By similarity). The transport activity is pH sensitive and Li(+) tolerant (PubMed:11243884). Moreover functions in both direction and is associated with large uncoupled fluxes of protons (By similarity). The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+) (By similarity). May have a particular importance for modulation of net hepatic glutamine flux (By similarity). |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:A2VCW5}; Multi-pass membrane protein. Note=Localized at astroglial membrane. {ECO:0000250|UniProtKB:A2VCW5} |
| Tissue Location | Predominantly expressed in stomach, brain, liver, lung and intestinal tract. |
Research Areas
Citations (0)
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Application Protocols
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$ 350.00
Cat# AP57960
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