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KCNK7 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, FC, E |
|---|---|
| Primary Accession | Q9Y2U2 |
| Other Accession | NP_005705.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 31947 Da |
| Antigen Region | 259-288 aa |
| Gene ID | 10089 |
|---|---|
| Other Names | Potassium channel subfamily K member 7, KCNK7 |
| Target/Specificity | This KCNK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-288 amino acids from the C-terminal region of human KCNK7. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | KCNK7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | KCNK7 |
|---|---|
| Function | Probable potassium channel subunit. No channel activity observed in vitro as protein remains in the endoplasmic reticulum. May need to associate with an as yet unknown partner in order to reach the plasma membrane. |
| Cellular Location | Membrane; Multi-pass membrane protein |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
KCNK7 is a member of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. Multiple transcript variants encoding different isoforms have been found for this gene.
References
Goldstein, S.A., et al. Pharmacol. Rev. 57(4):527-540(2005)
Goldstein, S.A., et al. Nat. Rev. Neurosci. 2(3):175-184(2001)
Medhurst, A.D., et al. Brain Res. Mol. Brain Res. 86 (1-2), 101-114 (2001) :
Salinas, M., et al. J. Biol. Chem. 274(17):11751-11760(1999)
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