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SNX25 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q9H3E2 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 98 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human SNX25 |
| Epitope Specificity | 521-620/840 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Endosome membrane; Peripheral membrane protein. Note=Detected in endosome-derived secreted vesicles (exosomes) from malignant pleural effusions. |
| SIMILARITY | Belongs to the sorting nexin family. Contains 1 PX (phox homology) domain. Contains 1 PXA domain. Contains 1 RGS domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Sorting nexin (SNX) proteins are members of a large family of hydrophilic PX (phospholipid-binding motif) domain-containing proteins that interact with a variety of receptor types. SNXs are widely expressed, although the tissue distribution of each SNX mRNA varies. The ability of SNXs to bind specific phospholipids, as well as their tendency to form protein-protein complexes, suggests a role for these proteins in cellular membrane trafficking and protein sorting. SNXs may also function specifically in pro-degradative sorting, internalization, endosomal recycling or simply in endosomal sorting. SNX25 (sorting nexin 25), also known as SBBI31 or MSTP043, is an 840 amino acid protein suggested to function in several stages of intracellular trafficking. A member of the sorting nexin family, SNX25 contains one PX (phox homology) domain, an RGS domain and one PXA domain. |
| Gene ID | 83891 |
|---|---|
| Other Names | Sorting nexin-25, SNX25 |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | SNX25 |
|---|---|
| Function | May be involved in several stages of intracellular trafficking. |
| Cellular Location | Endosome membrane; Peripheral membrane protein Note=Detected in endosome-derived secreted vesicles (exosomes) from malignant pleural effusions |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP58123
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