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AADACL1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q6PIU2 |
| Reactivity | Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45808 Da |
| Gene ID | 57552 |
|---|---|
| Other Names | Neutral cholesterol ester hydrolase 1, NCEH, 3.1.1.-, Arylacetamide deacetylase-like 1, NCEH1, AADACL1, KIAA1363 |
| Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | NCEH1 |
|---|---|
| Synonyms | AADACL1, KIAA1363 |
| Function | Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2- acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (PubMed:17052608). May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (By similarity). Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (By similarity). May contribute to cancer pathogenesis by promoting tumor cell migration (PubMed:17052608). |
| Cellular Location | Cell membrane; Single-pass type II membrane protein. Microsome {ECO:0000250|UniProtKB:Q8BLF1} |
| Tissue Location | Expressed in monocyte-derived macrophages. Up- regulated in invasive melanoma and breast carcinoma cell lines |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP58292
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