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ST3GAL5 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9UNP4 |
| Other Accession | NP_003887.3, NP_001035902.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 47990 Da |
| Antigen Region | 389-418 aa |
| Gene ID | 8869 |
|---|---|
| Other Names | Lactosylceramide alpha-2, 3-sialyltransferase, CMP-NeuAc:lactosylceramide alpha-2, 3-sialyltransferase, Ganglioside GM3 synthase, ST3Gal V, ST3GalV, Sialyltransferase 9, ST3GAL5, SIAT9 |
| Target/Specificity | This ST3GAL5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids of human ST3GAL5. |
| Dilution | FC~~1:10~50 IHC-P~~1:50~100 WB~~1:1000 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ST3GAL5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ST3GAL5 |
|---|---|
| Synonyms | SIAT9 |
| Function | Transfers the sialyl group (N-acetyl-alpha-neuraminyl or NeuAc) from CMP-NeuAc to the non-reducing terminal galactose (Gal) of glycosphingolipids forming gangliosides (important molecules involved in the regulation of multiple cellular processes, including cell proliferation and differentiation, apoptosis, embryogenesis, development, and oncogenesis) (PubMed:16934889, PubMed:9822625). Mainly involved in the biosynthesis of ganglioside GM3 but can also use different glycolipids as substrate acceptors such as D- galactosylceramide (GalCer), asialo-GM2 (GA2) and asialo-GM1 (GA1), although less preferentially than beta-D-Gal-(1->4)-beta-D-Glc-(1<->1)- Cer (LacCer) (PubMed:16934889). |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Ubiquitous. High expression in brain, skeletal muscle, placenta, and testis. mRNA widely distributed in human brain, but slightly elevated expression was observed in the cerebral cortex, temporal lobe, and putamen. |
Research Areas
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Application Protocols
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$ 150.00
$ 385.00
Cat# AP5834b
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