ZNF224 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q9NZL3 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 82280 Da |
Gene ID | 7767 |
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Other Names | Zinc finger protein 224, Bone marrow zinc finger 2, BMZF-2, Zinc finger protein 233, Zinc finger protein 255, Zinc finger protein 27, Zinc finger protein KOX22, ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | ZNF224 |
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Synonyms | BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
Function | May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. |
Cellular Location | Nucleus Note=Colocalizes with DEPDC1A at the nucleus |
Tissue Location | Ubiquitous. Mainly expressed in fetal tissues. |
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