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ZNF224 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q9NZL3 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 82 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human ZNF224 |
| Epitope Specificity | 101-200/707 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Nucleus. |
| SIMILARITY | Belongs to the krueppel C2H2-type zinc-finger protein family. Contains 18 C2H2-type zinc fingers. Contains 1 KRAB domain. |
| SUBUNIT | Interacts with WT1. Interacts with DEPDC1A. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 7767 |
|---|---|
| Other Names | Zinc finger protein 224, Bone marrow zinc finger 2, BMZF-2, Zinc finger protein 233, Zinc finger protein 255, Zinc finger protein 27, Zinc finger protein KOX22, ZNF224, BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
| Target/Specificity | Ubiquitous. Mainly expressed in fetal tissues. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | ZNF224 |
|---|---|
| Synonyms | BMZF2, KOX22, ZNF233, ZNF255, ZNF27 |
| Function | May be involved in transcriptional regulation as a transcriptional repressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells. |
| Cellular Location | Nucleus Note=Colocalizes with DEPDC1A at the nucleus |
| Tissue Location | Ubiquitous. Mainly expressed in fetal tissues. |
Citations (0)
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Application Protocols
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$ 385.00
Cat# AP58627
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