Allergin-1 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q7Z6M3 |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 38735 Da |
Gene ID | 284021 |
---|---|
Other Names | Allergin-1, Allergy inhibitory receptor 1, Mast cell antigen 32, MCA-32, Mast cell immunoglobulin-like receptor 1, MILR1, C17orf60, MCA32 |
Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MILR1 |
---|---|
Synonyms | C17orf60, MCA32 |
Function | Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction (By similarity). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Expressed in myeloid cells (dendritic cells, macrophages and neutrophils, weak expression on B-cells but not in T- cells or natural killer cells), peripheral blood basophils and mast cells (at protein level). |
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