TLR10/CD290 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF, ICC |
---|---|
Primary Accession | Q9BXR5 |
Reactivity | Rat, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 94564 Da |
Gene ID | 81793 |
---|---|
Other Names | Toll-like receptor 10, 3.2.2.6 {ECO:0000255|PROSITE-ProRule:PRU00204}, CD290, TLR10 |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | TLR10 |
---|---|
Function | Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Highly expressed in spleen, lymph node, thymus, tonsil and at lower levels in lung. Highly expressed in promyelocytic HL-60 cells and in B-cell lines |
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