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RhoGAP5 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, IHC-F, IF, ICC, E |
|---|---|
| Primary Accession | Q13017 |
| Reactivity | Rat, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 172 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human RhoGAP5 |
| Epitope Specificity | 251-350/1502 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cytoplasmic. |
| SIMILARITY | Contains 4 FF domains. Contains 1 Rho-GAP domain. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | Rho GTPase activating protein 5 negatively regulates RHO GTPases, a family which may mediate cytoskeleton changes by stimulating the hydrolysis of bound GTP. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Gene ID | 394 |
|---|---|
| Other Names | Rho GTPase-activating protein 5, Rho-type GTPase-activating protein 5, p190-B, ARHGAP5, RHOGAP5 |
| Target/Specificity | Expressed in kidney, brain, liver and lung. |
| Dilution | IHC-P=1:100-500,IHC-F=1:100-500,ICC=1:100-500,IF=1:100-500,ELISA=1:5000-10000 |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | ARHGAP5 |
|---|---|
| Synonyms | RHOGAP5 |
| Function | GTPase-activating protein for Rho family members (PubMed:8537347). |
| Cellular Location | Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also membrane-associated in a fibrillar pattern that colocalizes with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin. |
| Tissue Location | Detected in skin fibroblasts (at protein level) (PubMed:8537347). |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 385.00
Cat# AP58657
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