DHRS9 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF |
---|---|
Primary Accession | Q9BPW9 |
Reactivity | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 35227 Da |
Gene ID | 10170 |
---|---|
Other Names | Dehydrogenase/reductase SDR family member 9, 1.1.1.209, 1.1.1.53, 3-alpha hydroxysteroid dehydrogenase, 3-alpha-HSD, NADP-dependent retinol dehydrogenase/reductase, RDH-E2, RDHL, Retinol dehydrogenase 15, 1.1.1.105, Short chain dehydrogenase/reductase family 9C member 4, Short-chain dehydrogenase/reductase retSDR8, Tracheobronchial epithelial cell-specific retinol dehydrogenase, RDH-TBE, DHRS9, RDH15, SDR9C4 {ECO:0000303|PubMed:19027726} |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | DHRS9 |
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Synonyms | RDH15, SDR9C4 {ECO:0000303|PubMed:190277 |
Function | 3-alpha-hydroxysteroid dehydrogenase that converts 3-alpha- tetrahydroprogesterone (allopregnanolone) to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone (PubMed:11294878, PubMed:29541409). Also plays a role in the biosynthesis of retinoic acid from retinaldehyde (PubMed:11304534, PubMed:12618084). Can utilize both NADH and NADPH. |
Cellular Location | Microsome membrane. Endoplasmic reticulum membrane. Note=Associated with microsomal membranes |
Tissue Location | Highly expressed in trachea and epidermis. Detected at lower levels in spinal cord, bone marrow, brain, tongue, esophagus, heart, colon, testis, placenta, lung, skeletal muscle and lymph node |
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