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SEMCAP3 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
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Application 
| IHC-P, IHC-F, IF |
|---|---|
| Primary Accession | Q9UPQ7 |
| Reactivity | Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 119596 Da |
| Gene ID | 23024 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase PDZRN3, 2.3.2.27, Ligand of Numb protein X 3, PDZ domain-containing RING finger protein 3, RING-type E3 ubiquitin transferase PDZRN3, Semaphorin cytoplasmic domain-associated protein 3, Protein SEMACAP3, PDZRN3, KIAA1095, LNX3, SEMCAP3 |
| Dilution | Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200, |
| Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | PDZRN3 |
|---|---|
| Synonyms | KIAA1095, LNX3, SEMCAP3 |
| Function | E3 ubiquitin-protein ligase. Plays an important role in regulating the surface level of MUSK on myotubes. Mediates the ubiquitination of MUSK, promoting its endocytosis and lysosomal degradation. Might contribute to terminal myogenic differentiation. |
| Cellular Location | Synapse {ECO:0000250|UniProtKB:Q69ZS0}. Cytoplasm {ECO:0000250|UniProtKB:E7FDW2}. Note=Localizes to the postsynaptic region of neuromuscular junctions. {ECO:0000250|UniProtKB:Q69ZS0} |
| Tissue Location | Widely expressed, including in the heart, skeletal muscle and liver and, at lower levels, in the brain, colon, small intestine, placenta and lung. Down-regulated in ovarian serous papillary tumors. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 350.00
Cat# AP59176
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