CC85C Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | A6NKD9 |
| Reactivity | Rat, Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 45 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human CC85C |
| Epitope Specificity | 1-100/419 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Cell junction, tight junction (By similarity). Note=Localizes to the apical junction of radial glia in the wall of lateral ventricles of the developing brain (By similarity). Colocalizes with TJP1 on the meshwork-like structure of adherens junctions on the lateral ventricles wall (By similarity). |
| SIMILARITY | Belongs to the CCDC85 family. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Gene ID | 317762 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 85C, CCDC85C |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | CCDC85C |
|---|---|
| Function | May play a role in cell-cell adhesion and epithelium development through its interaction with proteins of the beta-catenin family (Probable). May play an important role in cortical development, especially in the maintenance of radial glia (By similarity). |
| Cellular Location | Cell junction, tight junction {ECO:0000250|UniProtKB:E9Q6B2}. Cell junction, adherens junction. Note=Localizes to the apical junction of radial glia in the wall of lateral ventricles of the developing brain Colocalizes with TJP1 on the meshwork-like structure of adherens junctions on the lateral ventricles wall {ECO:0000250|UniProtKB:E9Q6B2} |

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