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C11ORF77 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IHC-F, IF, E |
|---|---|
| Primary Accession | Q96MB7 |
| Reactivity | Rat, Pig, Dog, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 39 KDa |
| Physical State | Liquid |
| Immunogen | KLH conjugated synthetic peptide derived from human C11ORF77/HARBI1 |
| Epitope Specificity | 11-100/349 |
| Isotype | IgG |
| Purity | affinity purified by Protein A |
| Buffer | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| SUBCELLULAR LOCATION | Nucleus. Cytoplasm. Interaction with NAIF1 promotes translocation to the nucleus. |
| SIMILARITY | Belongs to the HARBI1 family. |
| SUBUNIT | Interacts with NAIF1. |
| Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| Background Descriptions | HARBI1 is a 349 amino acid nuclear and cytoplasmic protein belonging to the HARBI1 family. Members of the HARBI1 family of proteins are highly conserved in humans to various bony fish. Considered a transposase-derived protein, HARBI1 may possess nuclease activity and is expressed in brain, eye, nerve tissue, kidney and lung. HARBI1 utilizes divalent metal cations as cofactors, interacts with NAIF1 and promotes translocation to the nucleus. HARBI1 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| Gene ID | 283254 |
|---|---|
| Other Names | Putative nuclease HARBI1, 3.1.-.-, Harbinger transposase-derived nuclease, HARBI1, C11orf77 |
| Target/Specificity | Detected in brain, eye, nerve tissue, kidney and lung. |
| Dilution | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000 |
| Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
| Name | HARBI1 |
|---|---|
| Synonyms | C11orf77 |
| Function | Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. |
| Cellular Location | Nucleus. Cytoplasm. Note=Interaction with NAIF1 promotes translocation to the nucleus |
| Tissue Location | Detected in brain, eye, nerve tissue, kidney and lung. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
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$ 385.00
Cat# AP59429
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