C11orf65 Polyclonal Antibody
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, IHC-F, IF |
---|---|
Primary Accession | Q8NCR3 |
Reactivity | Rat, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 36720 Da |
Gene ID | 160140 |
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Other Names | Protein MFI, Mitochondrial fission factor interactor, MFI {ECO:0000303|PubMed:30059978}, C11orf65 |
Dilution | WB=1:500-2000,Elisa=1:500-1000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200, |
Format | 0.01M TBS(pH7.4), 0.09% (W/V) sodium azide and 50% Glyce |
Storage | Store at -20 ℃ for one year. Avoid repeated freeze/thaw cycles. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 ℃. |
Name | MFI {ECO:0000303|PubMed:30059978} |
---|---|
Synonyms | C11orf65 |
Function | Acts as an inhibitor of mitochondrial fission. Interacts with MFF and prevents DNM1L recruitment to mitochondria, promoting a more fused mitochondrial network. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9D4W2}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9D4W2}. Note=Predominantly localizes to the cytosol, with a minor fraction at the outer mitochondrial membrane {ECO:0000250|UniProtKB:Q9D4W2} |
Tissue Location | Enriched in the pancreatic beta cell and the testis and is expressed at low levels in other tissues tested |
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