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Anti-MNAT1 Antibody
Rabbit polyclonal antibody to MNAT1
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- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, IHC |
|---|---|
| Primary Accession | P51948 |
| Other Accession | P51949 |
| Reactivity | Human, Mouse, Rat, Pig, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35823 Da |
| Gene ID | 4331 |
|---|---|
| Other Names | CAP35; MAT1; RNF66; CDK-activating kinase assembly factor MAT1; CDK7/cyclin-H assembly factor; Cyclin-G1-interacting protein; Menage a trois; RING finger protein 66; RING finger protein MAT1; p35; p36 |
| Target/Specificity | Recognizes endogenous levels of MNAT1 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200), IP (1/10 - 1/100) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MNAT1 |
|---|---|
| Synonyms | CAP35, MAT1, RNF66 |
| Function | Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. |
| Cellular Location | Nucleus. |
| Tissue Location | Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human MNAT1. The exact sequence is proprietary.
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