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Anti-14-3-3 epsilon Antibody
Rabbit polyclonal antibody to 14-3-3 epsilon
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF/IC |
|---|---|
| Primary Accession | P62258 |
| Other Accession | P62259 |
| Reactivity | Human, Mouse, Rat, Zebrafish, Monkey, Chicken, Bovine, SARS |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 29174 Da |
| Gene ID | 7531 |
|---|---|
| Other Names | 14-3-3 protein epsilon; 14-3-3E |
| Target/Specificity | Recognizes endogenous levels of 14-3-3 epsilon protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | YWHAE |
|---|---|
| Function | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:35343654). Binding generally results in the modulation of the activity of the binding partner (By similarity). Positively regulates phosphorylated protein HSF1 nuclear export to the cytoplasm (PubMed:12917326). Plays a positive role in the antiviral signaling pathway upstream of TBK1 via interaction with RIGI (PubMed:37555661). Mechanistically, directs RIGI redistribution from the cytosol to mitochondrial associated membranes where it mediates MAVS-dependent innate immune signaling during viral infection (PubMed:22607805). Plays a role in proliferation inhibition and cell cycle arrest by exporting HNRNPC from the nucleus to the cytoplasm to be degraded by ubiquitination (PubMed:37599448). |
| Cellular Location | Nucleus. Cytoplasm Melanosome Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human 14-3-3 epsilon. The exact sequence is proprietary.
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$ 385.00
$ 195.00
Cat# AP59733
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