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Anti-LZK Antibody

Rabbit polyclonal antibody to LZK

     
  • WB - Anti-LZK Antibody AP59771
    Western blot analysis of LZK expression in EC9706 (A), SGC7901 (B), Panc1 (C), AML12 (D), rat brain (E), HepG2 (F), LO2 (G) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IP
Primary Accession O43283
Other Accession Q1HKZ5
Reactivity Human, Mouse, Rat, Rabbit, Chicken, Bovine, Drosophila
Host Rabbit
Clonality Polyclonal
Calculated MW 108296 Da
Additional Information
Gene ID 9175
Other Names LZK; Mitogen-activated protein kinase kinase kinase 13; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK
Target/Specificity Recognizes endogenous levels of LZK protein.
Dilution WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name MAP3K13 (HGNC:6852)
Function Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB- containing complex that phosphorylates inhibitors of NF-kappa-B.
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein
Tissue Location Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the center region of human LZK. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP59771
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