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Anti-B4GALT5 Antibody

Rabbit polyclonal antibody to B4GALT5

     
  • WB - Anti-B4GALT5 Antibody AP59777
    Western blot analysis of B4GALT5 expression in K562 (A), A549 (B), mouse heart (C), rat brain (D) whole cell lysates.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O43286
Other Accession Q9JMK0
Reactivity Human, Mouse, Rat, Monkey
Host Rabbit
Clonality Polyclonal
Calculated MW 45119 Da
Additional Information
Gene ID 9334
Other Names Beta-1, 4-galactosyltransferase 5; Beta-1, 4-GalTase 5; Beta4Gal-T5; b4Gal-T5; Beta-1, 4-GalT II; UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 5; UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 5
Target/Specificity Recognizes endogenous levels of B4GALT5 protein.
Dilution WB~~WB (1/500 - 1/1000)
Format Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide.
StorageStore at -20 °C.Stable for 12 months from date of receipt
Protein Information
Name B4GALT5 (HGNC:928)
Function Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer) (PubMed:24498430). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation (By similarity). Plays a role in the glycosylation of BMPR1A and regulation of its protein stability (By similarity). Essential for extraembryonic development during early embryogenesis (By similarity).
Cellular Location Golgi apparatus, Golgi stack membrane {ECO:0000250|UniProtKB:P15291}; Single-pass type II membrane protein Golgi apparatus {ECO:0000250|UniProtKB:A0A1S6M251}. Note=Trans cisternae of Golgi stack. {ECO:0000250|UniProtKB:P15291}
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)
citation

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Background

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human B4GALT5. The exact sequence is proprietary.

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$ 350.00
$ 175.00
Cat# AP59777
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