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Anti-TXNRD2 Antibody
Rabbit polyclonal antibody to TXNRD2
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9NNW7 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 56507 Da |
| Gene ID | 10587 |
|---|---|
| Other Names | KIAA1652; TRXR2; Thioredoxin reductase 2 mitochondrial; Selenoprotein Z; SelZ; TR-beta; Thioredoxin reductase TR3 |
| Target/Specificity | Recognizes endogenous levels of TXNRD2 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TXNRD2 (HGNC:18155) |
|---|---|
| Synonyms | KIAA1652, TRXR2 |
| Function | Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690). Maintains thioredoxin in a reduced state. May play a role in redox- regulated cell signaling. |
| Cellular Location | Mitochondrion. |
| Tissue Location | Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TXNRD2. The exact sequence is proprietary.
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