Anti-ATP6V1H Antibody
Rabbit polyclonal antibody to ATP6V1H
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
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Primary Accession | Q9UI12 |
Other Accession | Q8BVE3 |
Reactivity | Human, Mouse, Rat, Zebrafish, Monkey, Pig, Bovine |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 55883 Da |
Gene ID | 51606 |
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Other Names | V-type proton ATPase subunit H; V-ATPase subunit H; Nef-binding protein 1; NBP1; Protein VMA13 homolog; V-ATPase 50/57 kDa subunits; Vacuolar proton pump subunit H; Vacuolar proton pump subunit SFD |
Target/Specificity | Recognizes endogenous levels of ATP6V1H protein. |
Dilution | WB~~WB (1/500 - 1/1000), IP (1/10 - 1/100) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | ATP6V1H |
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Function | Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:33065002). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity). Subunit H is essential for V-ATPase activity, but not for the assembly of the complex (By similarity). Involved in the endocytosis mediated by clathrin-coated pits, required for the formation of endosomes (PubMed:12032142). |
Cellular Location | Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:O46563}; Peripheral membrane protein |
Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ATP6V1H. The exact sequence is proprietary.
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