Anti-APOA1BP Antibody
Rabbit polyclonal antibody to APOA1BP
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF/IC |
---|---|
Primary Accession | Q8NCW5 |
Other Accession | Q8K4Z3 |
Reactivity | Human, Mouse, Rat, Pig, Bovine, Drosophila |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 31675 Da |
Gene ID | 128240 |
---|---|
Other Names | AIBP; YJEFN1; NAD(P)H-hydrate epimerase; Apolipoprotein A-I-binding protein; AI-BP; NAD(P)HX epimerase; YjeF N-terminal domain-containing protein 1; YjeF_N1 |
Target/Specificity | Recognizes endogenous levels of APOA1BP protein. |
Dilution | WB~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | NAXE (HGNC:18453) |
---|---|
Function | Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) (PubMed:27616477). This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity). Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (PubMed:23719382). |
Cellular Location | Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03159}. Secreted {ECO:0000255|HAMAP-Rule:MF_03159, ECO:0000269|PubMed:11991719}. Note=In sperm, secretion gradually increases during capacitation. {ECO:0000255|HAMAP-Rule:MF_03159} |
Tissue Location | Ubiquitously expressed, with highest levels in kidney, heart and liver. Present in cerebrospinal fluid and urine but not in serum from healthy patients. Present in serum of sepsis patients (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human APOA1BP. The exact sequence is proprietary.
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