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Anti-TNFAIP1 Antibody
Rabbit polyclonal antibody to TNFAIP1
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q13829 |
| Other Accession | O70479 |
| Reactivity | Human, Mouse, Rat, Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 36204 Da |
| Gene ID | 7126 |
|---|---|
| Other Names | BACURD2; EDP1; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; hBACURD2; BTB/POZ domain-containing protein TNFAIP1; Protein B12; Tumor necrosis factor, alpha-induced protein 1, endothelial |
| Target/Specificity | Recognizes endogenous levels of TNFAIP1 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TNFAIP1 |
|---|---|
| Synonyms | BACURD2, EDP1 |
| Function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA- dependent DNA polymerase delta activity. |
| Cellular Location | Cytoplasm. Nucleus. Endosome. Note=Colocalizes with RHOB in endosomes |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human TNFAIP1. The exact sequence is proprietary.
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