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> home > Products > Primary Antibodies > Antibody Collections > GPCR Antibodies > Anti-Histamine H3 Receptor Antibody
Anti-Histamine H3 Receptor Antibody
Rabbit polyclonal antibody to Histamine H3 Receptor
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9Y5N1 |
| Other Accession | P58406 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 48671 Da |
| Gene ID | 11255 |
|---|---|
| Other Names | GPCR97; Histamine H3 receptor; H3R; HH3R; G-protein coupled receptor 97 |
| Target/Specificity | Recognizes endogenous levels of Histamine H3 Receptor protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | HRH3 |
|---|---|
| Synonyms | GPCR97 |
| Function | The H3 subclass of histamine receptors could mediate the histamine signals in CNS and peripheral nervous system. Signals through the inhibition of adenylate cyclase and displays high constitutive activity (spontaneous activity in the absence of agonist). Agonist stimulation of isoform 3 neither modified adenylate cyclase activity nor induced intracellular calcium mobilization. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Expressed predominantly in the CNS, with the greatest expression in the thalamus and caudate nucleus. The various isoforms are mainly coexpressed in brain, but their relative expression level varies in a region-specific manner. Isoform 3 and isoform 7 are highly expressed in the thalamus, caudate nucleus and cerebellum while isoform 5 and isoform 6 show a poor expression. Isoform 5 and isoform 6 show a high expression in the amygdala, substantia nigra, cerebral cortex and hypothalamus. Isoform 7 is not found in hypothalamus or substantia nigra |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Histamine H3 Receptor. The exact sequence is proprietary.
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$ 350.00
$ 175.00
Cat# AP60094
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