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Anti-HECW2 Antibody
Rabbit polyclonal antibody to HECW2
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IF/IC |
|---|---|
| Primary Accession | Q9P2P5 |
| Other Accession | Q6I6G8 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 175769 Da |
| Gene ID | 57520 |
|---|---|
| Other Names | KIAA1301; NEDL2; E3 ubiquitin-protein ligase HECW2; HECT, C2 and WW domain-containing protein 2; NEDD4-like E3 ubiquitin-protein ligase 2 |
| Target/Specificity | Recognizes endogenous levels of HECW2 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IF/IC (1/100 - 1/500) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | HECW2 |
|---|---|
| Synonyms | KIAA1301, NEDL2 |
| Function | E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle |
| Tissue Location | Predominantly expressed in adult brain, lung and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human HECW2. The exact sequence is proprietary.
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