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Anti-BGT-1 Antibody
Rabbit polyclonal antibody to BGT-1
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- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P48065 |
| Other Accession | P31651 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 69368 Da |
| Gene ID | 6539 |
|---|---|
| Other Names | Sodium- and chloride-dependent betaine transporter; BGT-1; Na(+)/Cl(-) betaine/GABA transporter; Solute carrier family 6 member 12 |
| Target/Specificity | Recognizes endogenous levels of BGT-1 protein. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | SLC6A12 (HGNC:11045) |
|---|---|
| Function | Transporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472). May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation. Probably also involved in renal and hepatic osmotic regulation (By similarity). |
| Cellular Location | Basolateral cell membrane {ECO:0000250|UniProtKB:P31651}; Multi-pass membrane protein. Cell membrane {ECO:0000250|UniProtKB:P31651}; Multi-pass membrane protein. Note=In kidney, locates in basolateral membranes of renal medulla. In liver, locates in hepatocytes cell membrane. {ECO:0000250|UniProtKB:P31651} |
| Tissue Location | Expressed in kidney, liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human BGT-1. The exact sequence is proprietary.
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