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Anti-FOXD3 Antibody
Rabbit polyclonal antibody to FOXD3
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9UJU5 |
| Other Accession | Q61060 |
| Reactivity | Human, Mouse, Rat, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 47630 Da |
| Gene ID | 27022 |
|---|---|
| Other Names | HFH2; Forkhead box protein D3; HNF3/FH transcription factor genesis |
| Target/Specificity | Recognizes endogenous levels of FOXD3 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/100 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/100 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | FOXD3 |
|---|---|
| Synonyms | HFH2 |
| Function | Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor (PubMed:11891324). Also acts as a transcriptional activator (PubMed:11891324). Negatively regulates transcription of transcriptional repressor RHIT/ZNF205 (PubMed:22306510). Promotes development of neural crest cells from neural tube progenitors (PubMed:11891324). Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation (PubMed:11891324). Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis (PubMed:11891324). |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in chronic myeloid leukemia, Jurkat T- cell leukemia and teratocarcinoma cell lines, but not in any other cell lines or normal tissues examined. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FOXD3. The exact sequence is proprietary.
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