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Anti-FTH1 Antibody
Rabbit polyclonal antibody to FTH1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB |
|---|---|
| Primary Accession | P02794 |
| Other Accession | P09528 |
| Reactivity | Human, Mouse, Rat, Rabbit, Monkey, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 21226 Da |
| Gene ID | 2495 |
|---|---|
| Other Names | FTH; FTHL6; Ferritin heavy chain; Ferritin H subunit; Cell proliferation-inducing gene 15 protein |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FTH1. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | FTH1 |
|---|---|
| Synonyms | FTH, FTHL6 |
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity (PubMed:9003196). Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (PubMed:9003196). Also plays a role in delivery of iron to cells (By similarity). Mediates iron uptake in capsule cells of the developing kidney (By similarity). Delivery to lysosomes is mediated by the cargo receptor NCOA4 for autophagic degradation and release of iron (PubMed:24695223, PubMed:26436293). |
| Cellular Location | Cytoplasm. Lysosome. Cytoplasmic vesicle, autophagosome |
| Tissue Location | Expressed in the liver. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human FTH1. The exact sequence is proprietary.
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