Anti-DHRS11 Antibody
Rabbit polyclonal antibody to DHRS11
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q6UWP2 |
Reactivity | Human, Rat, Monkey |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 28308 Da |
Gene ID | 79154 |
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Other Names | Dehydrogenase/reductase SDR family member 11 |
Target/Specificity | Recognizes endogenous levels of DHRS11 protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | DHRS11 |
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Synonyms | SDR24C1 {ECO:0000303|PubMed:19027726} |
Function | Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta- hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones. |
Cellular Location | Secreted. |
Tissue Location | Isoform 1: Ubiquitously expressed, with highest levels in testis, small intestine, colon, kidney, brain and heart Isoform 3: Expressed in brain, heart and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human DHRS11. The exact sequence is proprietary.
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