Anti-DOK7 Antibody
Rabbit polyclonal antibody to DOK7
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
---|---|
Primary Accession | Q18PE1 |
Other Accession | Q18PE0 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 53097 Da |
Gene ID | 285489 |
---|---|
Other Names | C4orf25; Protein Dok-7; Downstream of tyrosine kinase 7 |
Target/Specificity | Recognizes endogenous levels of DOK7 protein. |
Dilution | WB~~WB (1/500 - 1/1000) |
Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
Storage | Store at -20 °C.Stable for 12 months from date of receipt |
Name | DOK7 |
---|---|
Synonyms | C4orf25 |
Function | Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK. |
Cellular Location | Cell membrane; Peripheral membrane protein. Synapse. Note=Accumulates at neuromuscular junctions. |
Tissue Location | Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human DOK7. The exact sequence is proprietary.
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