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Anti-Hepassocin Antibody
Rabbit polyclonal antibody to Hepassocin
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q08830 |
| Other Accession | Q71KU9 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 36379 Da |
| Gene ID | 2267 |
|---|---|
| Other Names | HFREP1; Fibrinogen-like protein 1; HP-041; Hepassocin; Hepatocyte-derived fibrinogen-related protein 1; HFREP-1; Liver fibrinogen-related protein 1; LFIRE-1 |
| Target/Specificity | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Hepassocin. The exact sequence is proprietary. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/100) IHC~~1:100~500 |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | FGL1 {ECO:0000303|PubMed:18039467, ECO:0000312|HGNC:HGNC:3695} |
|---|---|
| Function | Immune suppressive molecule that inhibits antigen-specific T- cell activation by acting as a major ligand of LAG3 (PubMed:30580966). Responsible for LAG3 T-cell inhibitory function (PubMed:30580966). Binds LAG3 independently from MHC class II (MHC-II) (PubMed:30580966). Secreted by, and promotes growth of, hepatocytes (PubMed:11470158, PubMed:19880967). |
| Cellular Location | Secreted. Note=Secreted in the blood plasma |
| Tissue Location | Under normal conditions, liver-specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Hepassocin. The exact sequence is proprietary.
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