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Anti-E Cadherin (pS844) Antibody
Rabbit polyclonal antibody to E Cadherin (pS844)
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Application 
| WB |
|---|---|
| Primary Accession | P12830 |
| Other Accession | P09803 |
| Reactivity | Human, Mouse, Rat, Drosophila |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 97456 Da |
| Gene ID | 999 |
|---|---|
| Other Names | CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324 |
| Target/Specificity | Recognizes endogenous levels of E Cadherin (pS844) protein. |
| Dilution | WB~~WB (1/500 - 1/1000) E~~WB (1/500 - 1/1000) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CDH1 |
|---|---|
| Synonyms | CDHE, UVO |
| Function | Cadherins are calcium-dependent cell adhesion proteins (PubMed:11976333). They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells (PubMed:11976333). Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. |
| Cellular Location | Cell junction, adherens junction. Cell membrane; Single-pass type I membrane protein. Endosome. Golgi apparatus, trans-Golgi network. Note=Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in translocation from sites of cell-cell contact to the cytoplasm Colocalizes with RAB11A endosomes during its transport from the Golgi apparatus to the plasma membrane |
| Tissue Location | Non-neural epithelial tissues. |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human E Cadherin. The exact sequence is proprietary.
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$ 350.00
$ 175.00
Cat# AP61106
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