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Anti-Histone H1oo (AcK163) Antibody
Rabbit polyclonal antibody to Histone H1oo (AcK163)
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Application 
| WB, IHC |
|---|---|
| Primary Accession | Q8IZA3 |
| Other Accession | Q8VIK3 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 35813 Da |
| Gene ID | 132243 |
|---|---|
| Other Names | H1OO; OSH1; Histone H1oo; Oocyte-specific histone H1; Oocyte-specific linker histone H1; osH1 |
| Target/Specificity | Recognizes endogenous levels of Histone H1oo (AcK163) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | H1-8 (HGNC:18463) |
|---|---|
| Function | May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity). |
| Cellular Location | Cytoplasm. Nucleus {ECO:0000255|PROSITE-ProRule:PRU00837}. Chromosome {ECO:0000255|PROSITE-ProRule:PRU00837} |
| Tissue Location | Oocyte-specific.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Histone H1oo (AcK163). The exact sequence is proprietary.
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