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Anti-Thymidine Kinase 1 (pS13) Antibody
Rabbit polyclonal antibody to Thymidine Kinase 1 (pS13)
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Application 
| WB, IHC |
|---|---|
| Primary Accession | P04183 |
| Other Accession | P04184 |
| Reactivity | Human, Mouse, Rat, Bovine |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 25469 Da |
| Gene ID | 7083 |
|---|---|
| Other Names | Thymidine kinase cytosolic |
| Target/Specificity | Recognizes endogenous levels of Thymidine Kinase 1 (pS13) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | TK1 (HGNC:11830) |
|---|---|
| Function | Cell-cycle-regulated enzyme of importance in nucleotide metabolism (PubMed:9575153). Catalyzes the first enzymatic step in the salvage pathway converting thymidine into thymidine monophosphate (PubMed:22385435). Transcriptional regulation limits expression to the S phase of the cell cycle and transient expression coincides with the oscillation in the intracellular dTTP concentration (Probable). Also important for the activation of anticancer and antiviral nucleoside analog prodrugs such as 1-b-d-arabinofuranosylcytosine (AraC) and 3c- azido-3c-deoxythymidine (AZT) (PubMed:22385435). |
| Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human Thymidine Kinase 1 (pS13). The exact sequence is proprietary.
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