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Anti-CDC16 Antibody
Rabbit polyclonal antibody to CDC16
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- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q13042 |
| Other Accession | Q8R349 |
| Reactivity | Human, Mouse, Rat, Zebrafish |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 71656 Da |
| Gene ID | 8881 |
|---|---|
| Other Names | ANAPC6; Cell division cycle protein 16 homolog; Anaphase-promoting complex subunit 6; APC6; CDC16 homolog; CDC16Hs; Cyclosome subunit 6 |
| Target/Specificity | Recognizes endogenous levels of CDC16 protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | CDC16 |
|---|---|
| Synonyms | ANAPC6 |
| Function | Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle |
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human CDC16. The exact sequence is proprietary.
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