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Anti-NMDAR1 (pS890) Antibody
Rabbit polyclonal antibody to NMDAR1 (pS890)
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Application 
| WB, IF/IC, IHC |
|---|---|
| Primary Accession | Q05586 |
| Other Accession | P35438 |
| Reactivity | Human, Mouse, Drosophila |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 105373 Da |
| Gene ID | 2902 |
|---|---|
| Other Names | NMDAR1; Glutamate receptor ionotropic NMDA 1; GluN1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1 |
| Target/Specificity | Recognizes endogenous levels of NMDAR1 (pS890) protein. |
| Dilution | WB~~WB (1/500 - 1/1000), IH (1/50 - 1/200), IF/IC (1/100 - 1/500) IH~~WB (1/500 - 1/1000), IH (1/50 - 1/200), IF/IC (1/100 - 1/500) IF~~WB (1/500 - 1/1000), IH (1/50 - 1/200), IF/IC (1/100 - 1/500) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | GRIN1 |
|---|---|
| Synonyms | NMDAR1 |
| Function | Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+) (PubMed:7685113, PubMed:28126851, PubMed:26919761, PubMed:26875626, PubMed:28105280). Sensitivity to glutamate and channel kinetics depend on the subunit composition (PubMed:26919761). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Postsynaptic cell membrane. Postsynaptic density. Note=Enriched in postsynaptic plasma membrane and postsynaptic densities. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NMDAR1 (pS890). The exact sequence is proprietary.
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