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Anti-Collagen 17 alpha 1 Antibody
Rabbit polyclonal antibody to Collagen 17 alpha 1
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC |
|---|---|
| Primary Accession | Q9UMD9 |
| Other Accession | Q07563 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 150419 Da |
| Gene ID | 1308 |
|---|---|
| Other Names | BP180; BPAG2; Collagen alpha-1(XVII) chain; 180 kDa bullous pemphigoid antigen 2; Bullous pemphigoid antigen 2 |
| Target/Specificity | Recognizes endogenous levels of Collagen 17 alpha 1 protein. |
| Dilution | WB~~WB (1/500 - 1/2000), IH (1/50 - 1/200) IH~~WB (1/500 - 1/2000), IH (1/50 - 1/200) |
| Format | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | COL17A1 |
|---|---|
| Synonyms | BP180, BPAG2 |
| Function | May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. |
| Cellular Location | Cell junction, hemidesmosome. Membrane; Single- pass type II membrane protein. Note=Localized along the plasma membrane of the hemidesmosome [97 kDa linear IgA disease antigen]: Secreted, extracellular space, extracellular matrix, basement membrane Note=Localized in the lamina lucida beneath the hemidesmosomes |
| Tissue Location | Detected in skin (PubMed:8618013). In the cornea, it is detected in the epithelial basement membrane, the epithelial cells, and at a lower level in stromal cells (at protein level) (PubMed:25676728). Stratified squamous epithelia. Found in hemidesmosomes. Expressed in cornea, oral mucosa, esophagus, intestine, kidney collecting ducts, ureter, bladder, urethra and thymus but is absent in lung, blood vessels, skeletal muscle and nerves |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Collagen 17 alpha 1. The exact sequence is proprietary.
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