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Anti-Myeloperoxidase Antibody
Mouse monoclonal antibody to Myeloperoxidase
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC |
|---|---|
| Primary Accession | P05164 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Calculated MW | 83869 Da |
| Gene ID | 4353 |
|---|---|
| Other Names | Myeloperoxidase; MPO |
| Target/Specificity | Recognizes endogenous levels of Myeloperoxidase protein. |
| Dilution | IH~~IH (1/100 - 1/300) IF~~IH (1/100 - 1/300) |
| Format | Mouse IgG2b. Liquid in PBS containing 50% glycerol, 0.2% BSA and 0.09% (W/V) sodium azide. |
| Storage | Store at -20 °C.Stable for 12 months from date of receipt |
| Name | MPO (HGNC:7218) |
|---|---|
| Function | Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity (PubMed:9922160). Mediates the proteolytic cleavage of alpha-1-microglobulin to form t-alpha-1-microglobulin, which potently inhibits oxidation of low-density lipoprotein particles and limits vascular damage (PubMed:25698971). |
| Cellular Location | Lysosome. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
KLH-conjugated synthetic peptide encompassing a sequence within human Myeloperoxidase. The exact sequence is proprietary.
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