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CACNG5 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, IHC-P, E |
|---|---|
| Primary Accession | Q9UF02 |
| Other Accession | Q8VHW8, Q8VHW4 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 30903 Da |
| Antigen Region | 192-220 aa |
| Gene ID | 27091 |
|---|---|
| Other Names | Voltage-dependent calcium channel gamma-5 subunit, Neuronal voltage-gated calcium channel gamma-5 subunit, Transmembrane AMPAR regulatory protein gamma-5, TARP gamma-5, CACNG5 |
| Target/Specificity | This CACNG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the C-terminal region of human CACNG5. |
| Dilution | FC~~1:10~50 WB~~1:1000 IHC-P~~1:10~50 E~~Use at an assay dependent concentration. |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CACNG5 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CACNG5 |
|---|---|
| Function | Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity). |
| Cellular Location | Membrane; Multi-pass membrane protein. Postsynaptic density membrane |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
L-type calcium channels are composed of five subunits. The protein CACNG5 represents one of these subunits, gamma, and is one of several gamma subunit proteins. It is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state.
References
Chu,P.J., Gene 280 (1-2), 37-48 (2001)
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